2016 - IPTA Fellows Meeting


Mini-Oral Abstract Presentations

14.42 - Pediatric liver transplantation from living donors in cali - colombia

Presenter: Veronica, Botero, Cali, Colombia
Authors: veronica botero, Luis ArmandoLA CaicedoDr, Maria Teresa MT Agudelo, Eliana E Manzi, Jorge J Villegas, Gabriel JJ Echeverry, Oscar O Serrano


Pediatric liver transplantation from living donors in cali - colombia

veronica botero1, Luis Armando LA Caicedo Dr1, Maria Teresa MT Agudelo2, Eliana E Manzi3, Jorge J Villegas1, Gabriel J J Echeverry1, Oscar O Serrano 1.

1Liver trasplantation Unit, Fundación valle de Lili, Cali, Colombia; 2Intensive pediatric Care Unit, Fundación valle de Lili, cali, Colombia; 3Investigation Unit, Fundación valle de Lili, Cali, Colombia

Introduction Starting a pediatric liver transplant program in a developing country is a great challenge, due to technical difficulties and increased morbidity and mortality, and decreased graft survival.   The first liver transplant in children was performed in Fundación Valle del Lili (FVL) in 30 July 1996. During the first year of the program 2 to 7 transplants per year were carried out. Fundación Valle del Lili is a transplant referral center in Cali, South Western of Colombia. We describe here the experience and post-transplant survival in children, during two phases of our program. Methods. All patients transplanted between 31 July 1996 and 30 November 2014, from living donors were included. Follow up was performed every month during the first year and every 3 months afterwards. Phases of the program were defined as follows,  Phase 1 between 1996-2008, and Phase 2 between 2008-2014. Kaplan-Meier and Log Rank test were used for survival analysis. Results. Of the receptors, 41% (90/221) were transplanted from living donors. Six patients required retransplantation, 4 because of thrombosis of the hepatic artery, 1 due to thrombosis of the portal vein and 1 due to biliary duct stricture.  Fifty-two transplant recipients were girls (57%), median weight 7.5 Kilograms (IQR 6.5-10), median age 1 year (IQR 0,8 – 1.8).  Indications for liver transplant were atresia of biliary tract (74%) and fulminant hepatic failure (7%).  Survival after one year in Phase 1 and 2 was 60% (IC95% [43-74]) and 89% (IC95 [76-95]) respectively (p=0,0002), in recipients weighing less than 10 Kilograms survival were 48% (IC95% [27-65]) and 86% (IC95% [69-93]) in Phase 1 and 2 respectively (p<0.0001) . Regarding vascular complications, thrombosis of the hepatic artery was found in 12% of the entire group; although not stastically significant, there was an important reduction in thrombosis of the portal vein (26% vs. 6%).  Survival after 5 years was 89% in phase 2. Conclusions. There was a significant increase in survival, and less vascular complications in phase 2. Better survival could be attributed to greater surgical experience and larger number of patients being transplanted per year.


You must be logged in to view recordings

Important Disclaimer

By viewing the material on this site you understand and accept that:

  1. The opinions and statements expressed on this site reflect the views of the author or authors and do not necessarily reflect those of The Transplantation Society and/or its Sections.
  2. The hosting of material on The Transplantation Society site does not signify endorsement of this material by The Transplantation Society and/or its Sections.
  3. The material is solely for educational purposes for qualified health care professionals.
  4. The Transplantation Society and/or its Sections are not liable for any decision made or action taken based on the information contained in the material on this site.
  5. The information cannot be used as a substitute for professional care.
  6. The information does not represent a standard of care.
  7. No physician-patient relationship is being established.

Our Corporate Sponsors

TTS gratefully acknowledges the Corporate Partners whose generous support makes the work of the Society possible:

  • astellas
  • roche
  • sanofi