2011 - ISBTS 2011 Symposium


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Oral Communications 9: Psychosocial Outcomes & Quality of Life

12.209 - Male and female fertility after intestinal transplantation

Presenter: Juan Francisco, Guerra, Washington, United States
Authors: Juan Guerra1, Stephanie Kozlowski1, Cal Matsumoto1, Erin Fennelly1, Raffaele Girlanda1, Carrie Potoff1, Eddie Island1, Rohit Satoskar1, Jaqueline Laurin1, Kirti Shetty1, Veronica Gomez-Lobo1, Thomas Fishbein1

209
Male and female fertility after intestinal transplantation

Juan Guerra, Stephanie Kozlowski, Cal Matsumoto, Erin Fennelly, Raffaele Girlanda, Carrie Potoff, Eddie Island, Rohit Satoskar, Jaqueline Laurin, Kirti Shetty, Veronica Gomez-Lobo, Thomas Fishbein

Transplant Institute, Georgetown University Hospital, Washington, DC, United States

Successful pregnancies after solid organ transplantation have been reported, but minimal literature exists regarding fertility after intestinal transplantation (ITx). Little is known regarding the fertility effects on male ITx recipients, and only reported case of a successful female pregnancy has been reported.

We present our experience with pregnancies fathered by male ITx recipients and 1 female ITx recipient who is currently pregnant. Three males ITx recipients successfully fathered a child after transplant. Indications for ITx were short gut syndrome secondary to trauma, volvulus, and pseudobstruction. The mean age at the time of the transplant was 28 years old (range 26 -32). The interval between the ITx and paternity was 34.3 months (range 19-57), with a mean age of 29 (range 28 – 31) at the time of childbirth. No changes were made regarding their immunosuppressive (IS) therapy and currently all have healthy daughters ages 7, 6, and 1.5 years.

Currently, one of our female ITx recipients is pregnant at 16 weeks gestational age. She was found to be pregnant at the age of 26 years, 28 months after her transplant secondary to volvulus. IS has been maintained with tacrolimus and prednisone. The pregnancy has progressed with no complications, with normal obstetrical milestones.

Conclusion: Fertility after ITx is feasible for both male and female recipients. We believe this is an important aspect regarding quality of life of our ITx patients.

 


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