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2011 - CTS-IXA (Miami)

Parallel Session 1- Islets (Cell Track)

24 October 2011  /  10:30 - 12:30
3.107
Stimulation of VEGF secretion in rat pancreatic islets using Liraglutide
Presenter: Allan Langlois, Strasbourg, France
Authors: Allan Langlois1, Kevin Vivot1, Nathalie Jeandidier2,3, William Bietiger1, Camille Dollinger1, Michel Pinget1,2,3, Severine Sigrist1
3.110
Naturally pure islets for autotransplantation after total pancreatectomy for chronic pancreatitis
Presenter: Appakalai N. Balamurugan, Minneapolis, United States
Authors: A.N. Balamurugan1, Sajjad M. Soltani1, Melena D. Bellin1,2, Rachel Sutliff1, Gopalakrishnan Loganathan1, Klearchos K. Papas1, Bernhard J. Hering1, David E.R. Sutherland1

Parallel Session 2- Stem Cells (Cell Track)

24 October 2011  /  10:30 - 12:30
4.111
Pharmacologically active microcarriers enhance the therapeutic effects of MIAMI cell transplanted in hemi-parkinsonian rats
Presenter: Gaetan Delcroix, Miami, United States
Authors: Gaetan Delcroix1, Elisa Garbayo2, Laurence Sindji3, Olivier Thomas3, Claire Vanpouille-Box3, Gianluca D'Ippolito1, Claudia Montero-Menei3, Paul Schiller1
4.113
Pancreatic islets–derived Mesenchymal stromal cells can enter the pancreatic endocrine commitment but do not achieve consistent maturation
Presenter: Giacomo Lanzoni, Miami, United States
Authors: Giacomo Lanzoni1,2, Roberta Costa1, Francesco Alviano1, Cosetta Marchionni1, Giuseppe Cavallari3, Laura Foroni4, Gianandrea Pasquinelli5, Roberto Rimondini6, Laura Bonsi1, Riccardo Casadei3, Francesco Minni3, Camillo Ricordi2, Luca Inverardi2, Gian Paolo Bagnara1
4.116
Human amnion epithelial (hAE) stem cell transplant significantly improves phenotype and survival in a murine model of intermediate maple syrup urine disease (iMSUD)
Presenter: Kristen Skvorak, Pittsburgh, United States
Authors: Kristen Skvorak1, Kenneth Dorko1, Fabio Marongiu1, Veysel Tahan1, Marc Hansel1, Roberto Gramignoli1, Erland Arning2, Teodoro Bottiglieri2, Qin Sun3, K. Michael Gibson4, Stephen Strom1
4.118
Contact-dependent modulation of the human immune response to pig cells by adipose-derived mesenchymal stem cells (AdMSC) from GTKO/CD46 pigs
Presenter: Goutham Kumar, Pittsburgh, United States
Authors: Goutham Kumar1, Hidetaka Hara1, Cassandra Long1, David Ayares2, David K.C. Cooper1, Mohamed Ezzelarab1

Parallel Session 4- Innate Immunity, xenoantigens and antibodies (Xeno Track)

24 October 2011  /  10:30 - 12:30
6.130
Blocking porcine sialoadhesin improves extracorporeal porcine liver xenoperfusion
Presenter: Joshua Waldman, Toledo, United States
Authors: Joshua Waldman1, Thomas Vogel2, Peter Friend2, Michael Rees1
6.131
T cell-directed immunosuppression is associated with downregulation of thrombin activation, but upregulation of inflammatory responses in xenograft recipients
Presenter: Mohamed Ezzelarab, Pittsburgh, United States
Authors: Mohamed Ezzelarab1, Corin Ezzelarab1, Kumiko Isse1, Burcin Ekser1,2, Gabriel Echeverri3,4, David Ayares5, David Cooper1
6.132
Comparison of Gal and non-Gal mediated cardiac xenograft rejection
Presenter: Guerard Byrne, London, United Kingdom
Authors: Christopher McGregor1,2, Henry Tazelaar2, Guerard Byrne1,2
6.138
Study of complement activation in a life supporting pig to primate xenotransplantation model using GAL KO pigs
Presenter: Marta Vadori, Padova, Italy
Authors: Marta Vadori1, Moh Daha2, Ngaisah Klar2, Federica Besenzon1, Nicola Baldan3, Laura Cavicchioli4, Giulia Maria De Benedictis5, Massimo Boldrin1, Valentina Innocente1, Fabio Fante1, Fiorella Calabrese6, Gilles Blancho7, Pierre Giannello8, Cesare Galli9, Mark B. Nottle10, Peter Cowan11, Anthony J.F. D'Apice11, Emanuele Cozzi1,12
6.139
Rat elicited anti-carbohydrate xenoantibodies crossreact with cells of multiple species and bacteria
Presenter: Magdiel Pérez-Cruz, L'Hospitalet de Llobregat, Spain
Authors: Magdiel Pérez-Cruz1, Rafael Máñez1, Cristina Costa1

SOTA 2- Immunomodulation and Cell Based Strategies for Tolerance Induction (Cell Track)

24 October 2011  /  13:30 - 15:30
11.155
Chimerism
Presenter: Suzanne Ildstad, Louisville, United States
Authors: Suzanne Ildstad
11.156
Immune Regulation in Transplant Tolerance
Presenter: Ronald G. Gill, Aurora, United States
Authors: Ronald G. Gill

Parallel Session 8- Immunology (Immunoisolation) (Cell Track)

24 October 2011  /  16:00 - 18:00
14.199
High resolution, non-invasive longitudinal live imaging of immune responses
Presenter: Midhat H Abdulreda, Miami, United States
Authors: Midhat H. Abdulreda1, Gaetano Faleo1, R. Damaris Molano1, Maite Lopez-Cabezas1, Judith Molina1, Yaohong Tan3, Oscar Ron Echeverria1, Elsie Zahr-Akrawi1, Rayner Rodriguez-Diaz1, Patrick Edlund2, Ingo Leibiger2, Allison Bayer1, Victor Perez3, Camillo Ricordi1,2, Alejandro Caicedo1, Antonello Pileggi1, Per-Olof Berggren1,2
14.202
Influence of islet culture on angiogenic and inflammatory mechanisms
Presenter: Allan Langlois, Strasbourg, France
Authors: Allan Langlois1, Kevin Vivot1, Nathalie Jeandidier2,3, Camille Dollinger1, William Bietiger1, Michel Pinget1,2,3, Severine Sigrist1
14.206
Transplanted donor Treg cells can stably engraft leading to tolerance to allogeneic bone marrow cells in NOD mice
Presenter: Allison Bayer, Miami, United States
Authors: Cecilia Cabello2, Jackeline Chirinos1, Robert Levy1, Thomas Malek1, Allison L. Bayer1,2

Parallel Session 7- Bioengineering & Biomaterials (Cell Track)

24 October 2011  /  16:00 - 18:00
15.195
Silicone rubber membrane devices allow islet culture at 20 times the standard surface density with no adverse effects on viability, recovery, or potency
Presenter: Efstathios Avgoustiniatos, Lauderdale, United States
Authors: Efstathios S. Avgoustiniatos1, Phillip R. Rozak1, Kate R. Mueller1, Connor A. Lyons1, William E. Scott III1, Eric J. Falde1, Jennifer P. Kitzmann1, John R. Wilson2, Bernhard J. Hering1, Klearchos K. Papas1
15.197
Supporting islet transplant using polymer nanofiber scaffolds loaded with proangiogenic and immune suppressive compounds
Presenter: Daniel Bowers, Charlottesville, United States
Authors: Daniel Bowers2, Preeti Chhabra1, Linda Langman1, Edward Botchwey2, Kenneth Brayman1
15.198
Oxygen modulation in the culture of islets of Langerhans: the use of PFC-PDMS gas permeable membranes
Presenter: Christopher Fraker, Miami, United States
Authors: Christopher Fraker1, Kerim Gattas-Asfura1, Camillo Ricordi1, Luca Inverardi1, Juan Dominguez-Bendala1

Parallel Session 5- Islet Xenotransplantation - Preclinical Models (Xeno Track)

24 October 2011  /  16:00 - 18:00
16.172
Gal-knockout pigs transgenic for hCD46 and islet-specific TFPI/pCTLA4Ig have normal glucose metabolism and isolated islets exhibit normal glucose and arginine responses and should be considered as donors for islet xenotransplantation
Presenter: Martin Wijkstrom, Pittsburgh, United States
Authors: Martin Wijkstrom1, Suzanne Bertera2, Burcin Ekser1, Cassandra Long1, Hidetaka Hara1, Mohamed Ezzelarab1, Eefje Dons1, Goutham Kumar1, Dirk van der Windt1, Tatyana Votjakova2, Carol Phelps3, David Ayares3, David KC Cooper1, Rita Bottino2