TRIAGE FOR SIMULTANEOUS LIVER KIDNEY TRANSPLANTATION AND CLINICAL PEARLS TO OPTIMIZE RENAL PROTECTION AFTER LIVER TRANSPLANTATION
NOVEMBER 6, 2018 - 2 PM EST (MONTREAL TIME)
|Organizer: Sukru Emre, MD
Professor of Surgery (Transplant) and of Pediatrics, Yale University
New Haven, CT, USA
|Moderator: Marcelo Cantarovich, MD
Professor, Department of Medicine, Division of Nephrology, Faculty of Medicine, McGill University
Montréal, QC, Canada
|Discussant: Annmarie Huysman Liapakis, MD
Assistant Professor of Medicine (Digestive Diseases), Yale School of Medicine
New Haven, CT, USA
|Discussant: Clifford D. Miles, MD, MS, FAST
Associate Professor of Internal Medicine
University of Nebraska Medical Center
Omaha, NE, USA
TRANSPLANTATION DIRECT JOURNAL - HIGHLIGHTED ARTICLE
Dr Andrea Schlegel, Editorial Fellow, Transplantation.
Heavy Alcohol Use Among Decesased Donors Does Not Impact Recipient Outcomes After Liver Transplantation
Aurora SS, Chahal KS, Axley P, et al.
Transplantation. Published online April 19, 2018. DOI:10.1097/TP.0000000000002230.
With a lack of guidelines supporting decisions on the use of livers from donors with a history of alcohol intake, there are significant regional variations in organ discard rates among centers and some surgeons remain reluctant to consider such livers for transplantation.
Arora and others explored the impact of heavy donor alcohol consumption on outcomes after liver transplantation. Based on the UNOS database, 47 882 liver transplantations were included in this retrospective analysis. The authors perform propensity score matching (PMS) and compared 21 498 livers from "nonheavy drinkers" with 7166 grafts donated from "heavy drinkers" (defined as more than 2 drinks/dd.). Endpoints were graft and patient survival.
The authors found, that donor alcohol history alone had no impact on outcome after liver transplantation. Although further analyses may be required to define certain risk combinations, this report appears important to initiate a careful assessment and procurement processes in donors, despite positive alcohol history.
In conclusion, history of "heavy drinking" alone in deceased donors does not appear to impact on graft and patient survival after liver transplantation. Prospective studies will help to identify parameters predicting outcomes and to increase a safe utilization of livers from donors with a history of alcohol intake.
AbstracT Submission Now Open!
TTS-ILTS PAIRED TRANSPLANT CENTERS PROGRAM
Deadline January 1, 2019
The deadline to submit an application is JANUARY 1, 2019
The TTS-ILTS Paired Transplant Centers Program is a collaboration between The Transplantation Society (TTS) and the International Liver Transplantation Society (ILTS) supporting new liver transplant programs in emerging countries.
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