2015-2017 - Advanced Renal Transplantation - Interactive Teaching Series


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Recurrent and de novo Renal Disease

15.1 - Recurrent and de novo Renal Disease

Presenter: Anthony N. , Warrens, London, UK
Authors: Anthony N. Warrens

Learning Objectives:

  • Recurrent GN is the third most common cause of graft loss
  • It becomes more important later after transplantation
  • FSGS is the most common type and may respond to treatment
  • MCGN/MPGN has very high rate of recurrence and poor prognosis
  • Recurrent HUS has an especially poor outcome, depending on the underlying lesion
  • Recurrence of membranous and IgA nephropathy is often indolent with good prognosis
  • SLE and vasculitis have a low rate of recurrence
  • De novo FSGS has a poor prognosis but other de novo lesions usually progress slowly

Biography

Anthony Warrens trained in Glasgow, Oxford and London and undertook a postdoctoral fellowship in Boston, USA. He is currently Dean for Education, Professor of Renal and Transplantation Medicine and Director of the Institute of Health Sciences Education at Barts and The London School of Medicine and Dentistry, Queen Mary University of London. He is also Honorary Consultant Nephrologist at Barts Health NHS Trust where he maintains an active clinical practice. He is a non-executive director of Barking, Havering and Redbridge NHS University Trust and a member of the Human Tissue Authority. He is a past-President of the British Transplantation Society. His research interests include mechanisms of rejection and attitudes to organ donation in various communities. He is a Principal Fellow of the Higher Education Academy.


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