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2013 - IXA 2013 Congress (Osaka)
Oral Communication 2: Xeno Immunology - Tolerance and Cellular Immunity 11 November 2013 / 17:20 - 19:00
Initial evidence for functional immune modulation in primate recipients of porcine skin grafts following conditioning with human CD47 transgeneic pig hematopoietic stem cells Presenter: Aseda Tena, Seoul, United States		- Initial evidence for functional immune modulation in primate recipients of porcine skin grafts following conditioning with human CD47 transgeneic pig hematopoietic stem cells Presenter: Aseda Tena, Seoul, United States
Xenograft tolerance and immune functions of human T cells developing in pig thymus xenografts in humanized mice Presenter: Takashi Onoe, Seoul, Japan		- Xenograft tolerance and immune functions of human T cells developing in pig thymus xenografts in humanized mice Presenter: Takashi Onoe, Seoul, Japan
Long-term comparative study on the engraftment of human hematopoietic stem cells in sheep after xenogeneic in utero transplantation Presenter: Tomoyuki Abe, Seoul, Japan		- Long-term comparative study on the engraftment of human hematopoietic stem cells in sheep after xenogeneic in utero transplantation Presenter: Tomoyuki Abe, Seoul, Japan
Low and tapering dose of anti CD40 (2C10 or 3A8) for 8-week duration fails to extend GTKO.hCD46Tg pig to baboon cardiac xenograft survival beyond 5 months Presenter: Keith Horvath, Seoul, United States		- Low and tapering dose of anti CD40 (2C10 or 3A8) for 8-week duration fails to extend GTKO.hCD46Tg pig to baboon cardiac xenograft survival beyond 5 months Presenter: Keith Horvath, Seoul, United States
Pig to baboon heterotopic cardiac xenotransplantation: Potential role of baboon CD4+CD25Hi FOxP3+ T regulatory cells in long-term graft survival Presenter: Avneesh Singh, Seoul, United States		- Pig to baboon heterotopic cardiac xenotransplantation: Potential role of baboon CD4+CD25Hi FOxP3+ T regulatory cells in long-term graft survival Presenter: Avneesh Singh, Seoul, United States
Sensitization to nonGal antigens is significantly reduced in baboons with artery patch grafts from GTKO pigs transgenic for a mutant human MHC class II transactivator (CIITA) Presenter: Hayato Iwase, Seoul, United States		- Sensitization to nonGal antigens is significantly reduced in baboons with artery patch grafts from GTKO pigs transgenic for a mutant human MHC class II transactivator (CIITA) Presenter: Hayato Iwase, Seoul, United States
Porcine adipose-derived MSC might have a risk of enhancing T cell response, unlike human, mouse or rat MSC. Presenter: Kenta Iwasaki, Seoul, Japan		- Porcine adipose-derived MSC might have a risk of enhancing T cell response, unlike human, mouse or rat MSC. Presenter: Kenta Iwasaki, Seoul, Japan
Do pig mesenchymal stromal cells regulate human T cell responses to pig antigens through modulation of CD69 expression? Presenter: David K.C. Cooper, Seoul, United States		- Do pig mesenchymal stromal cells regulate human T cell responses to pig antigens through modulation of CD69 expression? Presenter: David K.C. Cooper, Seoul, United States
Poly I:C-activated monocytic suppressor cells suppress xenogenic cytotoxicity via IDO-dependent mechanisms Presenter: Akira Maeda, Seoul, Japan		- Poly I:C-activated monocytic suppressor cells suppress xenogenic cytotoxicity via IDO-dependent mechanisms Presenter: Akira Maeda, Seoul, Japan
Novel immumodulatory effects of extracorporeal photopheresis after heart transplantation Presenter: Markus J. Barten, Seoul, Germany		- Novel immumodulatory effects of extracorporeal photopheresis after heart transplantation Presenter: Markus J. Barten, Seoul, Germany
Oral Communication 3: Xeno Immunology - Non-Gal Antibodies and Coagulations (1) 11 November 2013 / 17:20 - 19:00
Expression of human coagulation-regulatory proteins on pig vascular endothelial cells reduces in vitro human platelet aggregation Presenter: Hayato Iwase, Nagoya, United States		- Expression of human coagulation-regulatory proteins on pig vascular endothelial cells reduces in vitro human platelet aggregation Presenter: Hayato Iwase, Nagoya, United States
Activated Protein C Modulates the Thrombotic Phenotype of Human Endothelial Protein C Receptor Transgenic Porcine Endothelium. Presenter: Donald Harris, Nagoya, United States		- Activated Protein C Modulates the Thrombotic Phenotype of Human Endothelial Protein C Receptor Transgenic Porcine Endothelium. Presenter: Donald Harris, Nagoya, United States
In vitro assessment of the compatibility of thrombomodulin and endothelial protein C receptor in the pig-to-human setting Presenter: Peter Cowan, Nagoya, Australia		- In vitro assessment of the compatibility of thrombomodulin and endothelial protein C receptor in the pig-to-human setting Presenter: Peter Cowan, Nagoya, Australia
Endothelial-specific expression of biological active human thrombomodulin in single-transgenic pigs and pigs with multiple genetic modifications Presenter: Annegret Wuensch, Nagoya, Germany		- Endothelial-specific expression of biological active human thrombomodulin in single-transgenic pigs and pigs with multiple genetic modifications Presenter: Annegret Wuensch, Nagoya, Germany
Control of procoagulant state using anticoagulant factor thrombomodulin in xenotransplantation Presenter: Yuko Miwa, Nagoya, Japan		- Control of procoagulant state using anticoagulant factor thrombomodulin in xenotransplantation Presenter: Yuko Miwa, Nagoya, Japan
The application of chimerism, small molecule inhibitors, and anti-idiotypic single chain antibodies to inhibit anti-non-gal xenoantibody responses. Presenter: John M. Stewart, Nagoya, United States		- The application of chimerism, small molecule inhibitors, and anti-idiotypic single chain antibodies to inhibit anti-non-gal xenoantibody responses. Presenter: John M. Stewart, Nagoya, United States
N-linked glycan profiling of GGTA1/CMAH knockout pigs identifies new potential carbohydrate xenoantigens Presenter: Chris Burlak, Nagoya, United States		- N-linked glycan profiling of GGTA1/CMAH knockout pigs identifies new potential carbohydrate xenoantigens Presenter: Chris Burlak, Nagoya, United States
N-glycolylneuraminic acid is strongly expressed in the pig cornea: relevance to corneal xenotransplantation Presenter: Hidetaka Hara, Nagoya, United States		- N-glycolylneuraminic acid is strongly expressed in the pig cornea: relevance to corneal xenotransplantation Presenter: Hidetaka Hara, Nagoya, United States
Development of anti-pig antibodies and characterization of B cell phenotype following wild-type pig-to-monkey corneal xenotransplantation Presenter: Hidetaka Hara, Nagoya, United States		- Development of anti-pig antibodies and characterization of B cell phenotype following wild-type pig-to-monkey corneal xenotransplantation Presenter: Hidetaka Hara, Nagoya, United States
Long-term IgG response to porcine Neu5Gc-antigens in burn patients treated with porcine skin xenografts Presenter: Yasuhiro Takeuchi, Nagoya, United Kingdom		- Long-term IgG response to porcine Neu5Gc-antigens in burn patients treated with porcine skin xenografts Presenter: Yasuhiro Takeuchi, Nagoya, United Kingdom
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2013 - IXA 2013 Congress (Osaka)

Oral Communication 2: Xeno Immunology - Tolerance and Cellular Immunity 11 November 2013 / 17:20 - 19:00

- Initial evidence for functional immune modulation in primate recipients of porcine skin grafts following conditioning with human CD47 transgeneic pig hematopoietic stem cells

- Xenograft tolerance and immune functions of human T cells developing in pig thymus xenografts in humanized mice

- Long-term comparative study on the engraftment of human hematopoietic stem cells in sheep after xenogeneic in utero transplantation

- Low and tapering dose of anti CD40 (2C10 or 3A8) for 8-week duration fails to extend GTKO.hCD46Tg pig to baboon cardiac xenograft survival beyond 5 months

- Pig to baboon heterotopic cardiac xenotransplantation: Potential role of baboon CD4+CD25Hi FOxP3+ T regulatory cells in long-term graft survival

- Sensitization to nonGal antigens is significantly reduced in baboons with artery patch grafts from GTKO pigs transgenic for a mutant human MHC class II transactivator (CIITA)

- Porcine adipose-derived MSC might have a risk of enhancing T cell response, unlike human, mouse or rat MSC.

- Do pig mesenchymal stromal cells regulate human T cell responses to pig antigens through modulation of CD69 expression?

- Poly I:C-activated monocytic suppressor cells suppress xenogenic cytotoxicity via IDO-dependent mechanisms

- Novel immumodulatory effects of extracorporeal photopheresis after heart transplantation

Oral Communication 3: Xeno Immunology - Non-Gal Antibodies and Coagulations (1) 11 November 2013 / 17:20 - 19:00

- Expression of human coagulation-regulatory proteins on pig vascular endothelial cells reduces in vitro human platelet aggregation

- Activated Protein C Modulates the Thrombotic Phenotype of Human Endothelial Protein C Receptor Transgenic Porcine Endothelium.

- In vitro assessment of the compatibility of thrombomodulin and endothelial protein C receptor in the pig-to-human setting

- Endothelial-specific expression of biological active human thrombomodulin in single-transgenic pigs and pigs with multiple genetic modifications

- Control of procoagulant state using anticoagulant factor thrombomodulin in xenotransplantation

- The application of chimerism, small molecule inhibitors, and anti-idiotypic single chain antibodies to inhibit anti-non-gal xenoantibody responses.

- N-linked glycan profiling of GGTA1/CMAH knockout pigs identifies new potential carbohydrate xenoantigens

- N-glycolylneuraminic acid is strongly expressed in the pig cornea: relevance to corneal xenotransplantation

- Development of anti-pig antibodies and characterization of B cell phenotype following wild-type pig-to-monkey corneal xenotransplantation

- Long-term IgG response to porcine Neu5Gc-antigens in burn patients treated with porcine skin xenografts

Oral Communication 2: Xeno Immunology - Tolerance and Cellular Immunity
11 November 2013 / 17:20 - 19:00

Oral Communication 3: Xeno Immunology - Non-Gal Antibodies and Coagulations (1)
11 November 2013 / 17:20 - 19:00