President’s Update

Deb SudanIn the last newsletter, I reported the endorsement by the membership (at the 2015 meeting in Buenos Aires, Argentina) for the change in the name of our Association.  The new name (Intestinal Rehabilitation and Transplant Association) more accurately reflects the commitment of our Association to multidisciplinary education and research along the entire continuum of care for patients with intestinal failure.  We are now actively planning the next meeting of IRTA and I ask that you mark your calendars, prepare your most significant observations and discoveries for abstract and poster presentations and plan to attend the Congress of the Intestinal Rehabilitation and Transplant Association (CIRTA 2017) in New York City June 28 – July 1, 2017.  Please visit the Congress website for more information about the exciting program that is planned ( 

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Nutritional Support in Intestinal Transplantation and Beyond
Thursday, September 8, 2016 – 10am Montreal time (3pm Birmingham, UK)

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Intestinal Rehabilitation and Transplantation Article Reviews

Macrochimerism in Intestinal Transplantation: Association with Lower Rejection Rates and Multivisceral Transplants, without GVHD. Zuber J, Rosen S, Shonts B, et al. Am J Trans 2015 Oct; 15(10):2691.

The authors, led by Tom Kato and Megan Sykes from Columbia University Medical Center in New York performed a comprehensive study on nine intestinal transplant recipients looking at the overall incidence of mixed chimerism after intestinal transplant and the association between mixed chimerism and graft rejection. T cell mixed chimerism was observed in 8 out of 9 isolated and multivisceral recipients and was far more frequent than the occurrence of GVHD -  which occurred in only one of the nine patients.  In addition, patients free of significant rejection had higher T cell chimerism both in frequency and absolute numbers.  The authors conclude that chimerism occurs more frequently in intestinal transplant recipients (particularly MVTx), without the negative effects of GVHD, and may be the explanation for the lower incidence of rejection in multivisceral recipients.

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Pediatric Intestinal Failure & Rehabilitation Symposium

The 9th International Pediatric Intestinal Failure & Rehabilitation Symposium (PIFRS) will take place on October 27-29th, 2016 at the UCLA Meyer and Renee Luskin Conference Center and Hotel in Los Angeles, CA. The organizers have put together a comprehensive agenda that includes all aspects of intestinal care including nutritional management, medical rehabilitation, surgical rehabilitation, and transplantation. There is a Pre-Symposium that will include an Allied Healthcare Symposium as well as a Primer designed to introduce the field to newcomers. The regular symposium will combine state-of-the-art lectures from leaders and innovators in the field to scientific presentation based on abstract submission. To date, a record number of abstract submissions have been received and reviewed. A record number of attendees have registered so far.

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