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Calendar
Calendar

2017 - IXA (Baltimore)

Plenary with a Spotlight on Young Investigators
23 September 2017  /  15:40 - 17:15

Anti-CD40 Antibody Mediated-Costimulation Blockade Promotes Long-Term Survival of full Thickness Corneal Xenotransplantation in Non-Human Primates

Presenter: Chang Ho Yoon, Seoul, Korea

- Anti-CD40 Antibody Mediated-Costimulation Blockade Promotes Long-Term Survival of full Thickness Corneal Xenotransplantation in Non-Human Primates

Presenter: Chang Ho Yoon, Seoul, Korea

Porcine GGTA1/B4GalNT2 Gene Knockout Reduces Antibody Binding and Achieves One Year Life-supporting Renal Xenograft in Pig-to-Rhesus Model

Presenter: Gregory Martens, Birmingham, United States

- Porcine GGTA1/B4GalNT2 Gene Knockout Reduces Antibody Binding and Achieves One Year Life-supporting Renal Xenograft in Pig-to-Rhesus Model

Presenter: Gregory Martens, Birmingham, United States

Generation of Anti-CD2 mAb-expressing GGTA1 Knock-in Pigs Using a High Fidelity CRISPR/Cas9 System

Presenter: Evelyn Salvaris, Fitzroy, Australia

- Generation of Anti-CD2 mAb-expressing GGTA1 Knock-in Pigs Using a High Fidelity CRISPR/Cas9 System

Presenter: Evelyn Salvaris, Fitzroy, Australia

Reducing the Inflammatory Response by Expressing Human Thrombomodulin in Pigs

Presenter: Hidetaka Hara, Birmingham, United States

- Reducing the Inflammatory Response by Expressing Human Thrombomodulin in Pigs

Presenter: Hidetaka Hara, Birmingham, United States

Human IL-10 Transfection of Porcine Lungs Significantly Increases IL-10 Levels in Vascular Perfusate During Human Blood Perfusion

Presenter: Christopher Laird, Baltimore, United States

- Human IL-10 Transfection of Porcine Lungs Significantly Increases IL-10 Levels in Vascular Perfusate During Human Blood Perfusion

Presenter: Christopher Laird, Baltimore, United States

Novel Technologies to Induce Tolerance
24 September 2017  /  07:30 - 08:30

Regulatory T Cells: From Allo to Xeno

Presenter: Mohamed Ezzelarab, Pittsburgh, United States

- Regulatory T Cells: From Allo to Xeno

Presenter: Mohamed Ezzelarab, Pittsburgh, United States

Mixed Chimerism: From Allo to Xeno

Presenter: David Sachs, Boston, United States

- Mixed Chimerism: From Allo to Xeno

Presenter: David Sachs, Boston, United States

Organ Xenotransplantation - Clinical and Preclinical Models
24 September 2017  /  08:30 - 09:30

hEPCR.hTBM.hCD47.HO-1 Contributes to Increased Survival, Reduced Platelet Sequestration, and modulation of Coagulation Activation in GalTKO.hCD46 Porcine Livers Perfused With Human Blood

Presenter: Arielle Cimeno, Baltimore, United States

- hEPCR.hTBM.hCD47.HO-1 Contributes to Increased Survival, Reduced Platelet Sequestration, and modulation of Coagulation Activation in GalTKO.hCD46 Porcine Livers Perfused With Human Blood

Presenter: Arielle Cimeno, Baltimore, United States

Physiologic Observations in Baboons with Life-Supporting Pig Kidney Grafts

Presenter: Hayato Iwase, Birmingham, United States

- Physiologic Observations in Baboons with Life-Supporting Pig Kidney Grafts

Presenter: Hayato Iwase, Birmingham, United States

CD4 Depletion Is Necessary and Sufficient For Long-Term Pig-To-Nonhuman Primate Renal Xenotransplant Survival

Presenter: Steven Kim, Atlanta, United States

- CD4 Depletion Is Necessary and Sufficient For Long-Term Pig-To-Nonhuman Primate Renal Xenotransplant Survival

Presenter: Steven Kim, Atlanta, United States

Histologically Proven Survival of Porcine Lung Xenografts in Baboons for Up To 10 Days Using Double Transgenic hCD47/hCD55 Galt-KO Donors

Presenter: Hironosuke Watanabe, , United States

- Histologically Proven Survival of Porcine Lung Xenografts in Baboons for Up To 10 Days Using Double Transgenic hCD47/hCD55 Galt-KO Donors

Presenter: Hironosuke Watanabe, , United States

The Roles of CD80 Upregulation and Human CD47 Expression on Glomerular Podocytes in Development of Proteinuria Following Pig-To Baboon Renal Xenotransplantation

Presenter: Kazuhiko Yamada, New York, United States

- The Roles of CD80 Upregulation and Human CD47 Expression on Glomerular Podocytes in Development of Proteinuria Following Pig-To Baboon Renal Xenotransplantation

Presenter: Kazuhiko Yamada, New York, United States

Xenoantigens and Antibodies
24 September 2017  /  08:30 - 09:30

Analysis of Non-gal Antibody Responses After Orthotopic Pig to Baboon Cardiac Xenotransplantation

Presenter: Guerard Byrne, London, United Kingdom

- Analysis of Non-gal Antibody Responses After Orthotopic Pig to Baboon Cardiac Xenotransplantation

Presenter: Guerard Byrne, London, United Kingdom

Swine Leukocyte Antigen Cross Reactive Group Antigens

Presenter: Gregory Martens, Birmingham, United States

- Swine Leukocyte Antigen Cross Reactive Group Antigens

Presenter: Gregory Martens, Birmingham, United States

In Vitro Immune Responses of HLA Highly-Sensitized and Non-sensitized Patients to Genetically-Engineered Pig Cells

Presenter: Zhongqiang Zhang, Pittsburgh, United States

- In Vitro Immune Responses of HLA Highly-Sensitized and Non-sensitized Patients to Genetically-Engineered Pig Cells

Presenter: Zhongqiang Zhang, Pittsburgh, United States

Potential Antigens Involved in Delayed Xenograft Rejection in a GGTA1/CMAH DKO Pig-to-Monkey Model

Presenter: Chengjiang Zhao, Shenzhen, People's Republic of China

- Potential Antigens Involved in Delayed Xenograft Rejection in a GGTA1/CMAH DKO Pig-to-Monkey Model

Presenter: Chengjiang Zhao, Shenzhen, People's Republic of China

Differential Response of Allo-/Xeno-Reactive CD4 T-Cells Against MHC Expressed in Endothelial Cells in the Presence of HLA, ABO, and Xeno (Gal and Nongal) Antibody

Presenter: Kenta Iwasaki, Nagakute, Japan

- Differential Response of Allo-/Xeno-Reactive CD4 T-Cells Against MHC Expressed in Endothelial Cells in the Presence of HLA, ABO, and Xeno (Gal and Nongal) Antibody

Presenter: Kenta Iwasaki, Nagakute, Japan

Identification of Novel Xenoreactive Non-Gal Antigens: Tetraspanin CD37 and CD81

Presenter: Burcin Ekser, Indianapolis, United States

- Identification of Novel Xenoreactive Non-Gal Antigens: Tetraspanin CD37 and CD81

Presenter: Burcin Ekser, Indianapolis, United States

Honorary Member Lecture & Presidential Address
24 September 2017  /  10:00 - 11:00

Introduction

Presenter: David Sachs, Boston, United States

- Introduction

Presenter: David Sachs, Boston, United States

Designing the Future Donor Organ (What Genes are Actually Needed?)
24 September 2017  /  12:00 - 13:45

Designing the Future Donor Organ (What Genes are Actually Needed?)

Presenter: Alfred Tector, Birmingham, United States

- Designing the Future Donor Organ (What Genes are Actually Needed?)

Presenter: Alfred Tector, Birmingham, United States