The Transplantation Society is a non-profit NGO providing global leadership in transplantation. Our core mission include the development of the science and clinical practice, scientific communication, continuing education and guidance on the ethical practice.

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Deadline is here - 24 hours left!

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Trainee Tracks Webinar

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NEW DATE Wednesday, February 28, 2018, 11am EST (Montreal time)

Topic: Making CME Matter: Innovative Solutions to Maximize the Impact of Medical Education

Speaker: Alexander S. Niven
Internal Medicine Program Director, Director of Medical Education and Research, and Designated Institutional Official at Madigan Army Medical Center in Tacoma, WA, USA

The goal of continuing medical education (CME) is to speed dissemination and adoption of best practices by physicians and their healthcare teams. Increasing focus on healthcare team performance and growing demands on their time and resources underlines the importance of efficient, effective CME opportunities. This webinar will discuss innovative CME solutions using current education design and active learning strategies, with practical examples using the collaborative experience of volunteer members and staff from the American College of Chest Physicians (CHEST). .

Click here for more information


Symposium in Organ Transplantation in Children

The International Pediatric Transplant Association is proud to feature a special section activity: the 2018 Symposium in Organ Transplantation in Children: An educational forum for physicians, surgeons, and allied health professionals.

The focus of this symposium is aimed at clinical and research fellows in pediatric solid organ transplantation, as well as residents, and other allied health professional or non-physician trainees who are planning a career in pediatric transplantation.

Click for details

IN THE NEWS


Scientists create functioning kidney tissue
February 9 - Scientists have successfully produced human kidney tissue within a living organism which is able to produce urine, a first for medical science.

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International Organ transplantation center to be established in Egypt
February 11 - Ministry of Health and Population will establish the biggest international organ transplantation center in the Middle East at El-Sheikh Zayed Al-Nahyan Hospital, Cairo, according to an official from the Ministry of Health.

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USA - DAAs Make Possible Transplant of HCV Positive Organs
February 9 - New research has reported that new DAA drugs may hold the key to making many more organs available to waiting patients.

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China - Researchers report first lung stem cell transplantation clinical trial

February 9 - A research team from Tongji University in China have made a breakthrough in human lung regeneration technology. For the first time, researchers have regenerated patients' damaged lungs using autologous lung stem cell transplantation in a pilot clinical trial.

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Long-Term Outcomes of Sirolimus in Maintenance Heart Transplant Recipients
February 8 - The authors [of the study] concluded that early conversion to SRL is associated with attenuated CAV progression as well as with lower long-term mortality and CAV-related events compared with continued CNI usage

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OneLegacy Announces Opening of California’s First Dedicated Transplant Recovery Center
February 7 - OneLegacy has announced the opening of California’s first dedicated Transplant Recovery Center designed to handle organ, eye and tissue donation and to provide renewed hope to the thousands waiting to receive the gift of life.

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Scientists develop a 'third eye' to examine stem cells
February 9 - A joint team of scientists from Russia and the United States designed a method for marking dividing stem cells with three different labels. Until now, it was only possible to use two labels simultaneously. The new method will increase the accuracy and speed of stem cell division analysis and reveal new populations of stem cells.

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2nd Opinion Leaders Meeting
on Stem Cell Derived Beta Cells
May 7-8, 2018 | Boston, MA, USA


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Workshop topics will include;
  • Identifying persistent challenges such as developing beta cells with full physiologic function
  • Understanding the potential role of genome engineering to modify cells for therapeutic advantage
  • Identifying optimal transplant platforms and encapsulation technologies
  • Developing effective approaches to escape allo-, and autoimmunity
  • Update on competing technologies including blastocyst complementation and gene edited xenografts
  • Presenting recent preclinical and clinical trial results.

Registration is now open, but capacity is limited. Register soon as you won't want to miss this opportunity.

Click here for more information and program details

Young Members Corner

Precision medicine in transplantation: the time is here

Jose Camargo Galvis Jose F Camargo, MD, University of Miami Miller School of Medicine, Young Members' Committee of The Transplantation Society

Transplantation is a rapidly evolving field of medicine. We live in an era of nanothechnology, gene microarray data, DNA sequencing, proteomics, epigenetic and microbiome. Biomarker-driven strategies are now being implemented in different areas of transplantation including donor matching; prediction of allograft survival and rejection; measurement of the net state of immunosuppression and other transplant outcomes. For example, microRNAs —small non-coding RNA molecules that regulate gene expression— are emerging as novel biomarkers for transplant outcomes including rejection and risk of cytomegalovirus (CMV) infection. High dimensional sequencing of DNA and RNA in donors and recipients offers the potential to improve donor-recipient matching by accounting for minor mismatches in the non-HLA domain. The use of bacteriophages —viruses that infect and replicate on bacteria— is being investigated for the management of resistant bacterial infections in high risk populations such as cystic fibrosis patients.

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Women in Transplantation - Call for Contributors

There has been a growing appreciation of the importance of sex and gender in transplantation research. However, good practice guidelines on study design and analysis when handling sex and gender issues in human transplantation research are missing. A scoping review of the literature is currently ongoing to synthesize the evidence on how sex and gender have been considered in human transplantation research to date. This review will help identify gaps and methodological concerns that may restrict the translation of transplantation research into clinical practice because of underestimation of sex/gender differences. The Women in Transplantation Initiative on issues of sex and gender in transplantation is looking to identify TTS members interested in leading a scoping/systematic review on issues of sex and gender in basic transplantation research. An excellent understanding of basic science methodologies is critical. People interested in contributing to this review are also needed. Interested individuals are invited to contact This email address is being protected from spambots. You need JavaScript enabled to view it. .

Transplantation Science Awards - Deadline May 31, 2018

The TTS Transplantation Science Committee together and Transplantation are pleased to announce the best manuscripts published by the journal in 2017. Named after two pioneering giants, a selection committee that included editors of Transplantation, The Transplantation Society, in addition to members and chairs of the Transplantation Science Committee will select two winners amongst a very competitive group of publications.

Click here for to nominate someone today!

TTS 2018 - Challenging Cases Competition

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Deadline: March 18, 2018

Are you involved in managing challenging transplant cases?
If yes, the Scientific Program Committee of the TTS 2018 congress in Madrid is inviting you to submit the most challenging case you were involved with.

The invitation is open to TTS and non-TTS members who are studying/training in any transplant related discipline (students, interns, residents, fellows or post-doctoral fellows). The submitters of the top three ranked cases will be invited to present these cases in a clinical crowdsourcing session at the post-graduate course (PGC) that will precede the TTS 2018 Congress. The winners will receive a complementary registration to the PGC and a Young Investigator Award of US $1000. Description of the case should not exceed 300 words.

CLICK HERE to submit your case!


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txdTID LARecommendations on travel medicine and the management of SOT recipients and donors: Latin America

Our journal, Transplantation, recently published this supplement with Guest Editor Wanessa Trindade Clemente. Topics included:

  • Chagas Disease Recommendations for Solid-Organ Transplant Recipients and Donors
  • Visceal and Cutaneous Leishmaniasis Recommendations for SOT Recipients and Donors
  • Malaria Disease Recommendations for SOT Recipients and Donors
  • Schistosomiasis and Strongyloidiasis Recommendations for Solid-Organ Transplant Recipients and Donors
  • Traveler’s Diarrhea Recommendations for SOT Recipients and Donors
  • Arboviruses Recommendations for Solid-Organ Transplant Recipients and Donors
  • Endemic Fungal Infection Recommendations for Solid-Organ Transplant Recipients and Donors
  • Tuberculosis Recommendations for SOT Recipients and Donors
  • Viral Hepatitis Recommendations for Solid-Organ Transplant Recipients and Donors
  • Vaccine Recommendations for Solid-Organ Transplant Recipients and Donors
  • Recommendations for Management of Endemic Diseases and Travel Medicine in SOT Recipients and Donors: Latin America – Map Gallery

Click here for to read this FREE issue


Trainee Tracks Webinar

niven

Tuesday, February 20, 2018, 10AM EST (MONTREAL TIME)

How to become an Educator

Speaker: Alexander S. Niven
Internal Medicine Program Director, Director of Medical Education and Research, and Designated Institutional Official at Madigan Army Medical Center in Tacoma, WA, USA

Click here for more information

Study: Data Sharing Practices in the Transplant Community

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February 7 - The Peter Morris Centre for Evidence in Transplantation are conducting an interesting study to investigate attitudes and current practices regarding anonymised clinical trial data sharing among Transplant professionals. This study will provide insight regarding the facilitators and barriers of sharing data and help develop better tools and processes for data sharing in the future. Participation in the survey will only take 5 minutes by clicking on this link:

Click here for more information


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Deadline is less than a week away!

It is anticipated that the compilation of late breaker abstracts is made possible by studies completed after the initial November 15, 2017 abstract submission deadline. They are intended to represent the very latest development in transplantation science. These abstracts will be reviewed in a very finite period by a special review board, and accepted with the same stringent criteria as the Nov 2017 abstract submissions. The review criteria will be at par with the original call for abstracts in Nov 2017, but for late-breaking abstracts there will be a stronger focus on the criteria of "very latest development in the field of transplantation".

CLICK HERE TO SUBMIT NOW

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FEATURED ARTICLE - Transplantation


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Submitted by Dr Andrea Schlegel, Editorial Fellow, Transplantation.

Normothermic Perfusion in the Assessment and Preservation of Declined Livers Before Transplantation: Hyperoxia and Vasoplegia-Important Lessons From the First 12 Cases.
Watson CJE, Kosmoliaptsis V, Randle LV, et al.
Transplantation. 2017 ;101(5):1084-1098

Cellular therapy using human regulatory macrophages (Mregs) to promote immune regulation is under evaluation in early phase clinical trials in kidney transplantation.

Christopher Watkins and co-workers from Cambridge report on their data of a normothermic preservation program using declined livers. The group assessed previously DCD (n=9) and DBD livers (n=3) after a median cold storage of 7.1 hrs on a normothermic perfusion device using a erythrocyte-based perfusate. Perfusion parameters and markers of liver injury and function were routinely measured, including mean arterial perfusion flow, arterial pO2, ALT- and lactate release and Glucose metabolism, cumulative bile production and bile ph. In addition, authors assessed cardiovascular stability of liver recipients after graft implantation including the amount of required inotropes and the rate of later biliary complications. The median perfusion duration was 4.7 hours. Though all twelve human livers achieved the current viability criteria during normothermic assessment, 5 recipients (in the first set of 6 livers) experienced a severe postreperfusion syndrome with sustained vasoplegia. Authors reduced therefore the oxygen tension during normothermic perfusion of the second set of livers (No.7-12). 11/12 patients are alive at a median of 12 months. This study demonstrates the potential of using normothermic preservation to increase the availability of livers for transplant. Avoiding hyperoxia may prevent postreperfusion syndrome and vasoplegia.

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starzlproze


The Thomas E. Starzl Transplantation Institute is accepting nominations for the 2018 Thomas E. Starzl Prize in Surgery and Immunology, awarded annually to a national or international leader in the field of organ transplantation and immunology.

Deadline May 1, 2018 - Click for details


Transplantation Science Awards - Deadline May 31, 2018

The TTS Transplantation Science Committee together and Transplantation are pleased to announce the best manuscripts published by the journal in 2017. Named after two pioneering giants, a selection committee that included editors of Transplantation, The Transplantation Society, in addition to members and chairs of the Transplantation Science Committee will select two winners amongst a very competitive group of publications.

Click here for to nominate someone today!


TTS 2018 - Challenging Cases Competition

challengingcases

Deadline: March 18, 2018

Are you involved in managing challenging transplant cases?
If yes, the Scientific Program Committee of the TTS 2018 congress in Madrid is inviting you to submit the most challenging case you were involved with.

The invitation is open to TTS and non-TTS members who are studying/training in any transplant related discipline (students, interns, residents, fellows or post-doctoral fellows). The submitters of the top three ranked cases will be invited to present these cases in a clinical crowdsourcing session at the post-graduate course (PGC) that will precede the TTS 2018 Congress. The winners will receive a complementary registration to the PGC and a Young Investigator Award of US $1000. Description of the case should not exceed 300 words.

CLICK HERE to submit your case!



IN THE NEWS


Game-changing kidney transplant technique developed in Toronto hospital

February 5 - For the first time in North America, a donated kidney has been successfully transplanted into a patient using a new system Selzner helped pioneer.

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Could this creature hold the future of regenerative medicine?

February 5 - Thanks to a team of scientists from UWA and Monash University, researchers are a step closer to understanding how mature cells (such as skin cells, brain cells or blood cells) can be reprogrammed back into stem cells in the laboratory.

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Landmark international study: CAR T-cell therapy safe and effective in youth with leukemia

January 31 - Results of the global, multicenter, pivotal phase 2 study that led to the first FDA approval of a gene therapy/cell therapy approach known as CAR T-cell therapy, were published today in the New England Journal of Medicine. The therapy, tisagenlecleucel, uses a patient's own white blood cells that have been genetically re-engineered to specifically target and kill cancer cells.

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Partial liver transplants have gotten safer for kids

February 8 - Alternatives to whole liver transplants have become safer for children, opening the way to shorter waitlists as more young patients receive portions of donated organs, a new study suggests.

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New target could minimise transplant risks

February 8 - From the discovery of this molecular mechanism, the group hopes to be able to develop new therapies for influencing inflammatory bowel inflammation after transplantation in order to further increase patients' chances of survival after stem cell transplantation.

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Expert Discusses Letermovir Approval for CMV Prophylaxis Post-Transplantation

Following allogeneic hematopoietic stem cell transplant (HSCT), the recently FDA-approved regimen letermovir (Prevymis) is highly recommended for high-risk patients with cytomegalovirus (CMV) infection, according to Miguel Perales, MD.

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NIH Blog - Creative Minds: Building Better Computational Models of Common Disease

February 8 - Not so long ago, Hilary Finucane was a talented young mathematician about to complete a master's degree in theoretical computer science. As much as she enjoyed exploring pure mathematics, Finucane had begun having second thoughts about her career choice. She wanted to use her gift for numbers in a way that would have more real-world impact.

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NIH Blog - Sequencing Human Genome with Pocket-Sized "Nanopore" Device

February 6 - It's hard to believe, but it's been almost 15 years since we successfully completed the Human Genome Project...

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Official Sections of The Transplantation Society

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Our Corporate Sponsors

TTS gratefully acknowledges the Corporate Partners whose generous support makes the work of the Society possible:

  • astellas
  • roche
  • sanofi