2013 - ISBTS 2013 Symposium

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Posters and Exhibition

15.62 - Evaluation of Post Intestinal Transplant Growth in Pediatric Patients

Presenter: Luis, Moulin, , Argentina
Authors: Maria Inés Martinez1, Carolina Rumbo1, Julio Trentadue2, Adriana Fernandez1, Gabriel Eduardo Gondolesi1

Evaluation of Post Intestinal Transplant Growth in Pediatric Patients

Maria Inés Martinez1, Carolina Rumbo1, Julio Trentadue2, Adriana Fernandez1, Gabriel Eduardo Gondolesi1

1Multiorgan Transplant Institute, Favaloro's Foundation University Hospital, Ciudad Autonoma de Buenos Aires, Argentina; 2Department of Pediatrics, Favaloro's Foundation University Hospital, Ciudad Autonoma de Buenos Aires, Argentina

Aim: to evaluate growth during the post intestinal transplant (ITX) period in a group of patients transplanted in the Centre between 05/2006 - 02/2012.
 Material and Methods: retrospective chart review describing the 12 pediatric patients surviving at present. We evaluate age at ITX, time from transplant to present and evolution of nutritional status measured at pre ITX evaluation (E), ITX, 1 and 2 years post ITX and at present, using A) z score for BMI and height/age (H/A). B) Growth velocity percentiles (p). C) Difference between points of zH/A.
Results:  Mean age at ITX was 7.38 ±4.1 years (r 1.5-12.5). Time from ITX to present was 3.8 ± 4.1 years (r 0.2-5.9).
A

 

Media/ standard deviation 
E
ITX
1 y post ITX
2 y post ITX
Present
zBMI
-0.67 ±1.49
-0.76 ±1.14
 
 
 -0.61  ±1.45
zH/A
-1.85 ±1.95
-1.88 ±1.98
-1.78 ±1.77
-2.01 ±1.36
-1.96 ±1.33
 
 B

 

Growth velocity/
Nº patients
Between E and ITX
1 y post ITX
2 y post ITX
< p 3
5
2
4
p 3-10
0
4
4
p 10 a 97
4
3
3
>p 97
2
2
1
 
C) The difference between points of zH/A at ITX and present is X 0.072 ±1.24 (r -1.26 to 2.56). In 6 patients zH/A worsened and it improved in 5. One patient is recently transplanted.
Conclusions: H/A pre ITX was deteriorated.
The follow up on zBMI and zH/A did not show significant differences in the studied period. There was no improvement on post ITX H/A. Nevertheless, considering patients individually, some patients showed improvement on zH/A when comparing ITX to present, showing periods of growth velocity recovery.

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