COMPLICATIONS - INFECTIONS

M.T. Arriola¹, J. Paladini², A. Gastaldi², A. Gomes¹, C. Favalli¹, J. Agusti¹, E. Cassini¹, P. Di rienzo¹, D. Yosse¹, L. Gaite^2
1Nefrology And Renal Transplant, clinica de nefrologia , urologia y enf. cardiovasculares, santa fe/ARGENTINA, ²Trasplante, clinica de nefrologia, santa fe/ARGENTINA

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Introduction

Until September 2009 in Argentina were confirmed 8384 cases of influenza pandemic N1H1. We present four confirmed cases of influenza A kidney active in a number of our transplant population.

Materials, methods and results:

A retrospective , descriptive study of four cases diagnosed Influenza N1 H1 by PCR in total population transplanted in our Center with includes renal graft I is conducted. Four patients had at thetime of infection normal renal function. The incidence was 0.6%. The sex ratio was 3: 1 in favour of men with an average age of 29.7 years. All of them had received transplantation with cadavericdonor and average time post transplant was 13.5 months (+/-1-38 months). Immunosuppression consisted of three schema with Anticalcineurínicos, Mycophenolate Mofetil and steroids. Signs,symptoms, radiological, need mechanical ventilation, time of hospitalization and death caused by infection were evaluated. At the time of the query, 100% of patients had shortness of breath, fever,tachypnea and productive cough. 75% Presented headache and asthenia and 50%, myalgia. All patients had respiratory semiology, bilateral crackles minerals and wheezing. Chest x-ray evidence bilateralin three cases interstitial pattern and interstitial alveoli in the remaining pattern. None of the patients required mechanical ventilation. They were treated with Oseltamivir for 10 days toFG-adjusted immediately before the clinical suspicion. The average hospital time was 8 days. Not be resgistró no death.

Conclusions

The incidence of influenza in our transplant population was low. The affected kidney transplant patients required hospitalization by serious acute respiratory infection. In spite of this clinicalevaluation is good and not reported death by this virus.

Disclosure: All authors have declared no conflicts of interest.