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2013 - IXA 2013 Congress (Osaka)

Oral Communication 2: Xeno Immunology - Tolerance and Cellular Immunity
11 November 2013  /  17:20 - 19:00

Initial evidence for functional immune modulation in primate recipients of porcine skin grafts following conditioning with human CD47 transgeneic pig hematopoietic stem cells

Presenter: Aseda Tena, Seoul, United States

- Initial evidence for functional immune modulation in primate recipients of porcine skin grafts following conditioning with human CD47 transgeneic pig hematopoietic stem cells

Presenter: Aseda Tena, Seoul, United States

Xenograft tolerance and immune functions of human T cells developing in pig thymus xenografts in humanized mice

Presenter: Takashi Onoe, Seoul, Japan

- Xenograft tolerance and immune functions of human T cells developing in pig thymus xenografts in humanized mice

Presenter: Takashi Onoe, Seoul, Japan

Long-term comparative study on the engraftment of human hematopoietic stem cells in sheep after xenogeneic in utero transplantation

Presenter: Tomoyuki Abe, Seoul, Japan

- Long-term comparative study on the engraftment of human hematopoietic stem cells in sheep after xenogeneic in utero transplantation

Presenter: Tomoyuki Abe, Seoul, Japan

Low and tapering dose of anti CD40 (2C10 or 3A8) for 8-week duration fails to extend GTKO.hCD46Tg pig to baboon cardiac xenograft survival beyond 5 months

Presenter: Keith Horvath, Seoul, United States

- Low and tapering dose of anti CD40 (2C10 or 3A8) for 8-week duration fails to extend GTKO.hCD46Tg pig to baboon cardiac xenograft survival beyond 5 months

Presenter: Keith Horvath, Seoul, United States

Pig to baboon heterotopic cardiac xenotransplantation: Potential role of baboon CD4+CD25Hi FOxP3+ T regulatory cells in long-term graft survival

Presenter: Avneesh Singh, Seoul, United States

- Pig to baboon heterotopic cardiac xenotransplantation: Potential role of baboon CD4+CD25Hi FOxP3+ T regulatory cells in long-term graft survival

Presenter: Avneesh Singh, Seoul, United States

Sensitization to nonGal antigens is significantly reduced in baboons with artery patch grafts from GTKO pigs transgenic for a mutant human MHC class II transactivator (CIITA)

Presenter: Hayato Iwase, Seoul, United States

- Sensitization to nonGal antigens is significantly reduced in baboons with artery patch grafts from GTKO pigs transgenic for a mutant human MHC class II transactivator (CIITA)

Presenter: Hayato Iwase, Seoul, United States

Porcine adipose-derived MSC might have a risk of enhancing T cell response, unlike human, mouse or rat MSC.

Presenter: Kenta Iwasaki, Seoul, Japan

- Porcine adipose-derived MSC might have a risk of enhancing T cell response, unlike human, mouse or rat MSC.

Presenter: Kenta Iwasaki, Seoul, Japan

Do pig mesenchymal stromal cells regulate human T cell responses to pig antigens through modulation of CD69 expression?

Presenter: David K.C. Cooper, Seoul, United States

- Do pig mesenchymal stromal cells regulate human T cell responses to pig antigens through modulation of CD69 expression?

Presenter: David K.C. Cooper, Seoul, United States

Poly I:C-activated monocytic suppressor cells suppress xenogenic cytotoxicity via IDO-dependent mechanisms

Presenter: Akira Maeda, Seoul, Japan

- Poly I:C-activated monocytic suppressor cells suppress xenogenic cytotoxicity via IDO-dependent mechanisms

Presenter: Akira Maeda, Seoul, Japan

Novel immumodulatory effects of extracorporeal photopheresis after heart transplantation

Presenter: Markus J. Barten, Seoul, Germany

- Novel immumodulatory effects of extracorporeal photopheresis after heart transplantation

Presenter: Markus J. Barten, Seoul, Germany

Oral Communication 3: Xeno Immunology - Non-Gal Antibodies and Coagulations (1)
11 November 2013  /  17:20 - 19:00

Expression of human coagulation-regulatory proteins on pig vascular endothelial cells reduces in vitro human platelet aggregation

Presenter: Hayato Iwase, Nagoya, United States

- Expression of human coagulation-regulatory proteins on pig vascular endothelial cells reduces in vitro human platelet aggregation

Presenter: Hayato Iwase, Nagoya, United States

Activated Protein C Modulates the Thrombotic Phenotype of Human Endothelial Protein C Receptor Transgenic Porcine Endothelium.

Presenter: Donald Harris, Nagoya, United States

- Activated Protein C Modulates the Thrombotic Phenotype of Human Endothelial Protein C Receptor Transgenic Porcine Endothelium.

Presenter: Donald Harris, Nagoya, United States

In vitro assessment of the compatibility of thrombomodulin and endothelial protein C receptor in the pig-to-human setting

Presenter: Peter Cowan, Nagoya, Australia

- In vitro assessment of the compatibility of thrombomodulin and endothelial protein C receptor in the pig-to-human setting

Presenter: Peter Cowan, Nagoya, Australia

Endothelial-specific expression of biological active human thrombomodulin in single-transgenic pigs and pigs with multiple genetic modifications

Presenter: Annegret Wuensch, Nagoya, Germany

- Endothelial-specific expression of biological active human thrombomodulin in single-transgenic pigs and pigs with multiple genetic modifications

Presenter: Annegret Wuensch, Nagoya, Germany

Control of procoagulant state using anticoagulant factor thrombomodulin in xenotransplantation

Presenter: Yuko Miwa, Nagoya, Japan

- Control of procoagulant state using anticoagulant factor thrombomodulin in xenotransplantation

Presenter: Yuko Miwa, Nagoya, Japan

The application of chimerism, small molecule inhibitors, and anti-idiotypic single chain antibodies to inhibit anti-non-gal xenoantibody responses.

Presenter: John M. Stewart, Nagoya, United States

- The application of chimerism, small molecule inhibitors, and anti-idiotypic single chain antibodies to inhibit anti-non-gal xenoantibody responses.

Presenter: John M. Stewart, Nagoya, United States

N-linked glycan profiling of GGTA1/CMAH knockout pigs identifies new potential carbohydrate xenoantigens

Presenter: Chris Burlak, Nagoya, United States

- N-linked glycan profiling of GGTA1/CMAH knockout pigs identifies new potential carbohydrate xenoantigens

Presenter: Chris Burlak, Nagoya, United States

N-glycolylneuraminic acid is strongly expressed in the pig cornea: relevance to corneal xenotransplantation

Presenter: Hidetaka Hara, Nagoya, United States

- N-glycolylneuraminic acid is strongly expressed in the pig cornea: relevance to corneal xenotransplantation

Presenter: Hidetaka Hara, Nagoya, United States

Development of anti-pig antibodies and characterization of B cell phenotype following wild-type pig-to-monkey corneal xenotransplantation

Presenter: Hidetaka Hara, Nagoya, United States

- Development of anti-pig antibodies and characterization of B cell phenotype following wild-type pig-to-monkey corneal xenotransplantation

Presenter: Hidetaka Hara, Nagoya, United States

Long-term IgG response to porcine Neu5Gc-antigens in burn patients treated with porcine skin xenografts

Presenter: Yasuhiro Takeuchi, Nagoya, United Kingdom

- Long-term IgG response to porcine Neu5Gc-antigens in burn patients treated with porcine skin xenografts

Presenter: Yasuhiro Takeuchi, Nagoya, United Kingdom

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TTS gratefully acknowledges the Corporate Partners whose generous support makes the work of the Society possible:

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