2014 - Transplant Infectious Disease Conference

This page contains exclusive content for the member of the following sections: TTS, TID. Log in to view.

Pesky Pathogens: Mycobacteria and Fungi

2.2 - TB and SOT in a heavily endemic region, and thoughts for less endemic regions

Presenter: Sang-Oh, Lee, Seoul, Korea
Authors: Sang-Oh Lee

Solid organ transplant (SOT) recipients have a significantly increased risk of developing infection with Mycobacterium tuberculosis compared with the general population. In a large Spanish cohort (RESITRA), the incidence of tuberculosis (TB) was 27-fold higher in SOT recipients than in the general population. It is difficult to recognize active TB in SOT recipients, since symptoms are often attenuated and the clinical presentations atypical. In a French multicenter retrospective cohort, 31% of all active TB cases after kidney transplantation (KT) were disseminated or 67% occurred at extra-pulmonary sites, compared to only about 20% of cases in normal hosts. Impediments to rapid and accurate diagnosis may lead to treatment delay. Therefore screening for latent tuberculosis infection (LTBI) in SOT candidates is important to prevent active TB diseases after transplantation.

Important Disclaimer

By viewing the material on this site you understand and accept that:

  1. The opinions and statements expressed on this site reflect the views of the author or authors and do not necessarily reflect those of The Transplantation Society and/or its Sections.
  2. The hosting of material on The Transplantation Society site does not signify endorsement of this material by The Transplantation Society and/or its Sections.
  3. The material is solely for educational purposes for qualified health care professionals.
  4. The Transplantation Society and/or its Sections are not liable for any decision made or action taken based on the information contained in the material on this site.
  5. The information cannot be used as a substitute for professional care.
  6. The information does not represent a standard of care.
  7. No physician-patient relationship is being established.



Staff Directory


The Transplantation Society
International Headquarters
740 Notre-Dame Ouest
Suite 1245
Montréal, QC, H3C 3X6