COMPLICATIONS - METABOLIC

M.R. Gumber¹, M. Gireesh¹, P.R. Shah¹, H.V. Patel¹, K.R. Goplani¹, T. Pandya¹, A.V. Vanikar², H.L. Trivedi^2
1Nephrology & Transplantation, Institute of kidney disease & Research Center.Dr H L Trivedi Institute of Transplantation Sciences, Ahmedabad/INDIA, ²Institute Of Transplantation Sciences, Institute of Kidney Disease and Research Centre, Ahmedabad/INDIA

Body: Aim: To study the effect of post transplant weight gain on renal allograft function Material and methods: This is a retrospective study wherein 94 patients with a minimum follow-up of 3 years were studied for the relationship of the weight gain at 1 year post transplant (expressed as percentage gain above the weight at 15days post transplant). Patients who expired or lost their grafts within a year of transplant were excluded from the study. Correlation was sought by using Pearson’s correlation coefficient. Results: The study included 81 males and 13 females. The mean age of the study group was 34±10.6 years .The average weight gain at the end of first post transplant year was19±16.4% . A negative correlation was observed between the weight gain and graft function. The correlation coefficient of weight gain with that of post transplant creatinine at the end of first, second and third years are -0.17. -0.18 and -0.08 respectively. Graft loss and mortality were observed to be highest with the group of patients who lost weight post transplant(23%) followed by the group which gained weight by more than 10% (16.7%) and least with the group who did not gain weight or gained less than 10% (8%). Conclusions: Malnutrition either in the form of weight loss or excessive weight gain is associated with higher graft loss/mortality and also relatively poor graft function.

Disclosure: All authors have declared no conflicts of interest.