2011 - 10th Meeting - IHCTAS
Plenary Session II. Part 1: Immunosuppression
3.2 - The Role of Donor Bone Marrow Chimerism in Promoting Acceptance of VCA
Presenter: Suzanne T., Ildstad, Louisville, KY, USA
Authors: Suzanne T. Ildstad
The Role of Donor Bone Marrow Chimerism in Promoting Acceptance of VCA
Suzanne T. Ildstad, Institute for Cellular Therapeutics, University of Louisville, Louisville, KY, USA.
1. Understanding of chimerism and tolerance
2. Status of current studies in chimerism in VCA
Vascularized Composite Allotransplants (VCA) are immunologically complex units, often comprised of a bone marrow component and microenvironment. Chimerism induces donor-specific tolerance. This presentation will highlight the role of donor bone marrow chimerism in promoting acceptance of VCA. It will provide a review of the current status of chimerism from bench to the bedside.
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