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2023-IPITA-IXA-CTRMS (San Diego, CA)

IPITA Pre-Congress: Successfully navigating difficult medical and surgical scenarios in Pancreas Transplantation
26 October 2023  /  09:00 - 12:00
Early technical complications
Presenter: Ty B. Dunn, United States
Immunologic allograft failure/pancreatectomy/retransplantation
Presenter: Jonathan Fridell, United States

Keynote Session: Opening Address and Keynote Lecture
26 October 2023  /  13:00 - 14:30
Advances in cell, tissue and organ engineering of interest to transplantation
Presenter: Paolo De Coppi, United Kingdom

Oral Abstract Session: Donor genetic modification for xenotransplantation 1
26 October 2023  /  14:45 - 15:45
Comparative analysis of survival rates between single GTKO and TKO pig to monkey kidney xenotransplantation
Presenter: Ik Jin Yun, Korea
Evaluation of expression of a human T-cell depleting monoclonal antibody in islets and other tissues of transgenic pigs
Presenter: Evelyn Salvaris, Australia
Deletion of additional iGb3s in GGTA1/B4GalNT2/CMAH knock-out pig reduces lymphocyte infiltration and tissue factor deposition in pig-to-cynomolgus arteriovenous fistula model
Presenter: Kyo Won Lee, Korea
Assessment of the immunological effect of multigene modification in donor pigs for xenotransplantation using a 3D-microfluidic in vitro model for the endothelium
Presenter: Mitra Gultom, Switzerland
Overexpression of hCD31 in porcine endothelial cells reduces neutrophil extracellular trap formation in human and non-human primates
Presenter: Suchen Kumar Yadav, Korea

Oral Abstract Session: Islet Transplantation: Engineering the Islet Site
26 October 2023  /  14:45 - 15:45
Islet allotransplantation into pre-vascularized Sernova Cell Pouch™ - Lessons learned from the first patient cohort.
Presenter: Piotr Witkowski, United States
Novel subcutaneous islet transplantation method using a bioabsorbable medical device to facilitate the guidance of the highly vascularized transplantation site
Presenter: Norio Emoto, Japan
Establishing an appropriate environment for subcutaneous islet transplantation; assessment of the optimal preparation period through the utilization bFGF-containing agarose rods
Presenter: Kei Yamane, Japan
Development of a novel method for measuring tissue oxygen pressure to improve the hypoxic condition in subcutaneous islet transplantation
Presenter: Hiroaki Mitsugashira, Japan
Bioengineered Omental Transplant Site Promotes Islet/Cell Survival in Non-human Primates
Presenter: Ji Lei, United States
Engineering a vascularized bioartificial pancreas for stem cell derived islet maturation
Presenter: Jonathan Brassard, Canada

Oral Abstract Session: Islet Xeno: Preserving graft integrity and evaluating the implant site
26 October 2023  /  14:45 - 15:45
Xenotransplantation of a novel immune-isolation device encapsulating porcine islets improved blood glucose levels in diabetic common marmosets without immunosuppressive drugs.
Presenter: Masayuki Shimoda, Japan
A novel subset of memory-like CD127highCD4+FOXP3+Treg found in porcine neonatal islet cell cluster (NICC) xenotransplant tolerant mice share similar features with tissue Tregs.
Presenter: Haina Wang, Australia
10-year follow-up of type 1 diabetic patients following an encapsulated porcine islet xenotransplantation without immunosuppression
Presenter: Shinichi Matsumoto, Japan
CD40-specific costimulation blockade and rapamycin prevent porcine islet-xenograft rejection in nonhuman primates through regulation of B and T cell xenoreactivity
Presenter: Amar Singh, United States
Spatial transcriptomic analysis on the liver of pig to NHP islet transplantation recipients reveals increased adipogenesis and non-alcoholic fatty liver disease pathway in early post-transplantation
Presenter: Yoon Ji Bang, Korea

Oral Abstract Session: Pre-clinical and clinical application of xenotransplantation and current barriers 1
26 October 2023  /  14:45 - 15:45
Auxiliary liver xenotransplantation technique in a transgenic pig-to-non-human primate model: A surgical approach to prolong survival
Presenter: Kyo Won Lee, Korea

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