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The detailed program, faculty and abstracts are now available online!

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Hotel reservations are available here - Book early as space is limited!

Plenary Spotlight

Sessions Spotlight


CME for Utilizing a CDST for Resistant/Refractory CMV in SOT Patients

Watch the new video and earn CME!

Join Drs. Kotton, Razonable, and Humar as they illustrate how to use a new clinical decision support tool (CDST) for resistant or refractory cytomegalovirus (CMV) infection in solid organ transplant (SOT) patients. They will walk you through a challenging CMV resistant patient case and demonstrate how to enter clinical data into the novel CDST for optimal treatment decision making. An expert panel discussion provides opportunity for you to learn how to apply the CDST in practice and incorporate a new therapy, maribavir, into the care of SOT patients with resistant or refractory CMV infection.

GLOBAL REPORT ON ORGAN DONATION AND TRANSPLANTATION 2020

Beatriz Dominguez-Gil, Spain
Director General
National Transplant Organization
TTS Past Councilor (Europe)

Dear colleagues and friends,

I am delighted to present you the 2020 Global report, the most comprehensive report that we have prepared so far, including data and information extracted from the Global Observatory on Donation and Transplantation (GODT).

On the one hand, this report presents the activity data on donation and transplantation at global, regional and country level, and also shows data related to the organ waiting lists, and donation and transplantation practices compared to the previous year, before the pandemic (2019).

I would like to highlight that the report addresses some pieces of information about legal aspects and organizational systems in place. This is the first time that this type of data are presented from 104 contributing Member States.

Introduction

The Global Observatory on Donation and Transplantation (GODT) is the result of a collaborative effort between the World Health Organization (WHO) and the Spanish Organización Nacional de Trasplantes (ONT). The GODT was created in 2006 in response to World Health Assembly Resolution 57.18 requesting the Director General of the WHO to collect global data on the practices, safety, quality, efficacy, epidemiology and ethical issues of allogeneic transplantation. This request was further emphasized in Resolution 63.22 that also urged Member States to collaborate in the collection of such data. The GODT compiles global activity data on organ donation and transplantation, as well as country descriptions of legislations and regulatory oversights in place.
The Council of Europe Newsletter Transplant database and other international data collections, such as that performed by countries of the Iberoamerican Council/Network of Donation and Transplantation (RCIDT), are connected with the GODT to avoid duplication of efforts.
The aim of this report is to provide an overview of the current legislative and organizational situation of donation and transplantation in the world, as well as of organ donation and transplantation activities in the year 2020, a year marked by the COVID-19 pandemic.

TTC Public Workshop - September 22, 2022 @ 8AM ET

Since 2017 TTS has been participating in the Transplantation Therapeutics Consortium (TTC), a program of the Critical Path Institute.

Accelerating medical product development in kidney transplantation through a public-private partnership

This public workshop will be focusing on 1) qualifying a composite surrogate for long-term graft loss after kidney transplantation 2) real-world evidence (RWE) use in transplant clinical trials and 3) potential future endpoints in kidney transplantation The Transplant Therapeutics Consortium (TTC) aims to accelerate the medical product development process for transplantation by identifying challenges, prioritizing solutions, and developing tools to advance new product development to meet the most pressing needs of transplant recipients.
Click to view the agenda
Welcoming remarks
Session 1: Qualifying a composite surrogate for long-term graft loss after kidney transplantation
  • Regulatory qualification procedures and qualification status of the iBox Scoring System as a reasonably likely surrogate endpoint with FDA
  • Graphical user interface for sample size calculation using iBox scores
  • Panel discussion
Session 2: RWE use in transplant clinical trials
  • Regulatory and design considerations for RWE supplementation in transplant clinical trials
  • Pilot study for external control using the cyclosporine arm of the BENEFIT RCT versus UNOS/OPTN registry data
  • Sample size calculation and use RWE for supplemental external controls for the 5-year survival analyses
  • Panel discussion
Session 3: Future endpoints in kidney transplantation
  • Efficacy endpoints
  • Safety endpoints
  • Regulatory qualification procedures for clinical outcome assessments
  • Patient-reported outcome measures for transplantation
  • Panel discussion
Closing Remarks

TTS Needs Assessment Survey

This survey focuses on issues encountered by physicians in day-to-day decision-making.

Your responses will aid TTS in developing strategies, programs and resources to better improve access and transparency in transplantation, with an emphasis on increasing deceased donor organ transplantation.

The information collected will also aid the work TTS is doing as part of our World Health Organization collaboration.

All responses will be kept confidential and anonymous.

The survey will take 6+ minutes and must be done from a computer or tablet.

ISVCA 2022 Recap and Congress Videos

15th ISVCA Congress in Cancun, Mexico, a Big Success!

The 15th Congress of the International Society for Vascularized Composite Allotransplantation (ISVCA) was successfully held in Cancun, Mexico (June 4-6, 2022). The theme of the meeting was “Miracle and Magic of VCA.”

More than 400 participants from 21 countries participated in the Congress, of which the scientific program of the main congress spanned two days of sessions. These highlighted world updates in VCA, including successful outcomes and complications as well as progress in experimental research and innovative advances with clinical impact. Special breakout sessions included those on psychosocial aspects, economics, bioethical dilemmas and policy considerations in the field.

Abstracts were submitted from various VCA centers across the world, including promising clinical studies, experimental work on transplant immunology, and novel strategies for immunomodulation and graft surveillance. Seven (7) abstracts were selected for the prestigious TTS Abstract Travel Awards.

TTS Abstract Travel Award Winners:
Claudio Francisco Reyes Montero
Isabel Arenas Hoyos
Ibrahim Natalwala
Arimelek Córtes Hernández
Aldo Giovanni Beltrán Pardo
Aileen X Escobar Hernández
Juan Pablo Reyes González
Read More
DR. CURTIS CETRULO
President, ISVCA
Harvard Medical School
United States

Congress recordings are available to ISVCA and TTS members in english and spanish translation!
Congress attendees will receive an email with their access next week!

Transplantation Updates

Transplantation - Featured Most Downloaded Paper

IN VIEW: PEOPLE IN TRANSPLANTATION - Beatriz Dominguez-Gil

Question: As the Director General of the Spanish National Transplant Organization (ONT), you oversee the world’s most recognized organ Donation and Transplantation structure, the Spanish Model. What is the secret of your and the organization’s success?

Response: It is common to believe that convincing the population to donate is the fundamental aspect for increasing deceased donation rates. However, when donation is low in a given jurisdiction, this is not because of the people; it is because the healthcare system is doing something wrong. These are not my words, but those of my predecessor as Director of ONT, Dr Rafael Matesanz.1 This was very early understood in Spain: the key for success to increase organ donation—and transplant opportunities—is an exquisite management of the process of deceased donation, a process of high complexity ...

Don't miss meeting Beatriz at the TTS 2022 (click for details)

Transplantation - Highlighted Tweet

Clinical Characteristics and Outcomes of Kidney Transplant Recipients With SARS-CoV-2 Reinfections

Get informed about COVID-19 reinfection after kidney transplantation by the study by Basic-Jukic et al. From their work, it is clear that further work is urgently needed to better understand #COVID reinfections. .

Transplantation Direct - Higlighted Articles

@MonaDoshiMD et al. studied the potential impact of removing race from kidney donor risk index (KDRI) calculator in response to recent events of racial injustice.

The Role of Donor Sex in Females Undergoing Repeat Kidney Transplant: Does Prior Donor Sex Matter?


Women in Transplantation & Asian Society of Transplantation - Fellowship Grant

Women in Transplantation is delighted to announce that they will co-sponsor a research fellowship grant with the Asian Society of Transplantation.
- Deadline is August 25, 2022-

The Asian Society of Transplantation will fund a research project that contributes to our understanding of the impact of sex and/or gender in transplantation using “Asian Society Transplant Registry-Women in transplantation-kidney transplantation (ASTREG-WIT-KT) data.”

ASTREG-WIT-KT is an online registry for data collection and analysis of gender disparity across Asia-Pacific countries. It was borne out of WIT's Pillar 2, which focuses on sex and gender research as it related to solid organ transplantation.

Any epidemiologic, clinical studies using this data will be considered for this grant.


Recording now available! TTS-Women in Nephrology - India


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