Transplantation Updates

Just Released - Transplantation - April 2023 Issue

There are some great overviews in this month addressing Eplet matching, Klotho, transplantation in patients with Sickle Cell disease and a thoughtful review of the relationships between infection and rejection. There is attention to increasing the use of marginal donors including livers from donors with abdominal trauma and with Hepatitis C. The science of organ perfusion continues to advance across organs from lungs to kidneys. New knowledge on managing cardiac, islet and uterine transplants ensure that there is something for everyone in this issue.

Table of Contents

Around the World

Research Highlights

Game Changer

People in Transplantation

Special Article

Meeting Report


Transplantation - Highlighted Tweets

Thrombotic microangiopathy (TMA) is a rare and devastating complication of kidney transplantation, which often leads to graft failure. Posttransplant TMA (PT-TMA) may occur either de novo or as a recurrence of the disease. De novo TMA can be triggered by immunosuppressant drugs, antibody-mediated rejection, viral infections, and ischemia/reperfusion injury in patients with no evidence of the disease before transplantation. Recurrent TMA may occur in the kidney grafts of patients with a history of atypical hemolytic uremic syndrome (aHUS) in the native kidneys.

Trifecta ( #NCT04239703) is a prospective trial defining relationships between donor-derived cell-free DNA (dd-cfDNA), donor-specific antibody (DSA), and molecular findings in kidney transplant biopsies. Previous analyses of double results showed dd-cfDNA was strongly associated with rejection-associated molecules in the biopsy. The present study analyzed the triple results in 280 biopsies, focusing on the question of dd-cfDNA levels in DSA-negative antibody-mediated rejection (AMR).

Transplantation Direct - Highlighted Tweet

Normothermic regional perfusion (NRP) has gained widespread adoption in multiple European countries. The aim of this study was to examine the influence of thoracoabdominal-NRP (TA-NRP) on the utilization and outcomes of liver, kidney, and pancreas transplantation in the United States.

Following the outbreak of coronavirus disease 2019 (COVID-19) in the United States, the number of kidney waitlist additions and living-donor and deceased-donor kidney transplants (LDKT/DDKT) decreased substantially but began recovering within a few months. Since then, there have been several additional waves of infection, most notably, the Delta and Omicron surges beginning in August and December 2021, respectively.

2023 Organ Donation Congress (ISODP 2023)

Last week to submit your abstract for the ISODP 2023 Congress!

Register Today for ITS 2023!

The hotel is almost sold out! Book your room ASAP!

Join us in Niagara-on-the-Lake and contribute to an exciting and stimulating scientific meeting that will inspire and challenge you!

Announcement - 41st Annual Scientific meeting (ASM) of TSANZ

Dear Colleagues,

We are delighted to announce and invite you to “save the date” for the 41st Annual Scientific meeting (ASM) of the Transplantation Society of Australia and New Zealand (TSANZ) which will be held from Sunday 18 – Tuesday 20th June 2023 at the Brisbane Convention and Exhibition Centre in beautiful and sunny Brisbane, Queensland.

The TSANZ Scientific Program and Education Committee (SPEC), in conjunction with the TSANZ Council, have prepared an exciting program convened by Dr Chandima Divithotawela and A/Professor Antiopi Varelias.

This year's program features Plenary sessions from several renowned international speakers on recent advances in the areas of transplant immunology, xenotransplantation, emerging cellular therapies, chronic rejection and organ donation. Not limited to this, the program will also span transplant genetics, cutting-edge basic science topics, ethical issues of transplantation and will include a Women in Transplant (WIT) session.

As with previous years, this year, we are delighted to host three pre-ASM sessions including:

  • an HLA Day on Friday 16th June (convened by Dr Lucy Sullivan and Rhonda Holdsworth)
  • the Postgraduate Course on Saturday 17th June (convened by Dr Jennifer Li and Dr Handoo Rhee)
  • the Masterclass on Sunday 18th June (convened by Steven Hiho and Dr Georgina Irish).

The annual Awards dinner with live entertainment will be held in the iconic Brisbane City Hall, a short stroll along the Victoria Bridge over the stunning Brisbane River. Besides networking opportunities, several social events are planned by the TSANZ Early Career Researcher Committee (ECRC) including:

  • the annual Fun Run
  • Early Career researchers' drinks after the PGC on Saturday
  • “Meet a Researcher” event

We look forward to welcoming you to Australia’s River City in June 2023 for what will be an exceptional and exciting meeting!

Dr Chandima Divithotawela

A/Professor Antiopi Varelias

TSANZ ia an Affiliated Society of TTS

IPITA-IXA-CTRMS 2023 Joint Congress

The Joint Congress organizers are pleased to announce that the abstract submission deadline has now been EXTENDED to May 4th at midnight ET.

Abstract Submission Information:
  • Submission deadline: May 4, 2023
  • Notification of acceptance: June 20, 2023
  • Registration: Presenters must be registered and have paid their registration fee by July 24, 2023; otherwise, the abstract will be removed from the program.
  • ONLY accepted abstracts by a presenter registered to attend the Congress will be published in an online supplement of the Transplantation Journal.
  • It is the submitter’s responsibility to ensure that all co-authors approve of the abstract’s submission, publication, and potential presentation.

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