The December issue of Transplantation Direct is out and ready for viewing. This issue contains reports in kidney transplantation on outcomes in older recipients that experienced COVID-19, and on a risk scoring system for predicting post-transplant diabetes. In liver transplantation, an experience and lessons-learned is presented on establishing a hypothermic oxygenated perfusion program in a real-life setting of the South American country, Brazil. For those interested in heart transplantation, we have articles on a new model to predict post-transplant infections, and on factors associated with sinoatrial reinnervation after transplantation. Organ donation issues also are brought into focus, where outcomes following “therapeutic kidney donation" are evaluated, and the impact of ICU staff attitudes on donation are assessed. As the year comes to a close, we welcome you to visit the Transplantation Direct website for open access to all the details of these studies.