Investigators have identified 2 distinct populations at high risk for graft loss after kidney transplantation. Risk factors at baseline suggest approaches to management, according to investigators.
Among 5752 solitary kidney transplants performed 2006-2018, graft loss occurred in 21.6% of patients, including 9.6% with graft failure and 12.0% with death with a functioning graft (DWFG).
Reference: Merzkani MA, Bentall AJ, Smith BH, et al. Death with function and graft failure after kidney transplantation: Risk factors at baseline suggest new approaches to management. Transplantation Direct. 8(2):e1273. doi:10.1097/TXD.0000000000001273
UNOS data suggest interaction by age and mode of brain death
Hearts donated after death from stroke presented a higher mortality risk to the recipient if the donor was under age 40, a study showed.
In terms of recipient mortality, an analysis of the United Network for Organ Sharing (UNOS) registry showed no overall effect of stroke as a cause of donor brain death on outcomes, similar to what other contemporary series have shown.
However, there was more to it, with a "nonintuitive" interaction by donor age (P=0.008), reported Shinobu Itagaki, MD, MSc, of Mount Sinai Medical Center in New York City, and colleagues in the Journal of the American College of Cardiology.
— But little effect on graft, patient survival rates
Use of advanced preoperative 3D planning for pediatric liver transplant patients receiving larger grafts was associated with lower risk of postoperative complications, a small retrospective study in Taiwan found.
— The brain-organ connection is complex. Here’s what surgeons look for before, during and after a transplantation.
Livers outnumber people in Catherine Kling’s operating room at the University of Washington Medical Center. On this particular day, the extra organ — the only one ex-vivo, cleaned and sitting on ice — arrived just hours before the transplantation, the culmination of a thoughtful and time-consuming process of diagnoses, donor locating, evaluations and transportation, all sequenced by many expert pairs of eyes and hands.
Recognized as the world's highest dedicated award for the most outstanding contributions in the field of transplantation.
THE INTERNATIONAL TRANSPLANTATION SCIENCE MENTEE-MENTOR AWARDS FOR THE 29TH INTERNATIONAL CONGRESS OF THE TRANSPLANTATION SOCIETY (TTS 2022) – BUENOS AIRES, ARGENTINA, SEPTEMBER 10-14, 2022.
The Transplantation Society celebrates the contributions of basic science to the field of transplantation with the International Transplantation Science Mentee-Mentor Awards to recognize the efforts of scientists who have advanced our understanding of transplantation science and fostered the development of the young investigators who will be the future leaders in our field.
The application will open in January 2022. Deadline for submission is April 10, 2022.Click here for more details
As the global leader in transplantation, committed to health and life for all, The Transplantation Society expresses grave concern over the escalating violence and humanitarian crisis in Ukraine.
The protection of civilians and preservation of healthcare is imperative. TTS stands ready to support our colleagues, friends, families and patients impacted by this tragedy. As a non-State actor in official relations with the World Health Organization, we will seek collaborate with the WHO to provide our expert assistance on the Ukraine emergency
We are monitoring the situation and have setup a donation page (https://ukraine.tts.org) to collect funds to be distributed to support the maintenance of healthcare in the Ukraine and assist transplant patients as may be possible. We will also reach out to contacts to assess how we can assist to re-establish transplantation activities once the crisis has ended. TTS will match each contribution, dollar for dollar, up to $50,000 USD in total.